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In use for more than a decade, Orchid Cellmark's SNP technology is one of the most validated SNP scoring methods available today. Orchid Cellmark's patented SNP method involves a set of biochemical reactions that isolates the precise location of a suspected SNP and then simply and directly determines the identity of the SNP, using an enzyme called DNA polymerase.
DNA polymerase helps give our SNP technology its exceptional accuracy. And because Orchid Cellmark's technology is a direct method of determining the identity of a SNP, it is both more accurate and more robust than techniques that indirectly infer the SNP's presence. Accuracy is essential in SNP scoring, as even a 1% error rate could result in huge numbers of incorrect findings when analyzing large numbers of patient samples. This high level of accuracy also contributes to the cost effectiveness of Orchid Cellmark's SNP technology. Orchid Cellmark's SNP technology is also very versatile. The SNP analyses produced by the reaction can be "read-out" using a variety of instrument systems, including many already widely used by researchers. And the technology serves equally well whether running a single SNP score on a few dozen samples or thousands of SNP scores on tens of thousands of samples.
Orchid Cellmark currently uses SNP technology in its agriculture DNA testing business and in particular applications in forensics where DNA samples are highly degraded. Orchid Cellmark uses Short Tandem Repeats, or STRs, in its forensic and family relationship DNA testing services. For more information on STRs and SNPs, click here.
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